The drug Ibuprofen is used as an analgesic and anti-inflammatory drug for the treatment of rheumatoid arthritis (including juvenile rheumatoid arthritis or Still's disease), ankylosing spondylitis, osteoarthritis and other non-rheumatoid (seronegative) arthropathies. Ibuprofen is indicated for the treatment of non-rheumatic inflammatory processes of mixed periarticular tissues, such as the "frozen" shoulder (inflammation of the joint's lining), bursitis, tendonitis, tendovaginitis, and low back pain. Ibuprofen can also be used to relieve high pain syndrome with the damage of soft tissue, such as sprain. Ibuprofen is also indicated as an anesthetic drug for the relieving of a mild and moderate pain syndrome in the conditions such as dysmenorrhea, dental or postoperative pain, for the symptomatic relief of headache, including migraine headaches.
According to revievs of cannabis users, taking Ibuprofen together with weed is safe. Also it is noted that mixing Ibuprofen and weed cannot decrease your high.
Application Method And The Dosage
The drug is taken orally, preferably between food intakes (it is not recommended to mix it with food). In order to minimize the risks of developing side effects, the patients should take minimal effective doses of the drug Ibuprofen and it should be taken during the shortest period necessary to achieve a clinical effect.
Ibuprofen MAX is prescribed to the adult patients, as well as children over 12 years old and weighing 40 kg or more.
The dosage is set individually and depends on the indications. Usually to adults and children over 12 years old (body weight of 40 kg or more) Ibuprofen is prescribed in an initial dose of 400 mg 1-2 times a day, and, if it’s necessary, to achieve a therapeutic effect, the dose can be higher - 400 mg 3 times a day. It is not recommended to take more than 3 tablets in 24 hours (1200 mg).
In case of missing the dose of the drug, it is recommended to take the dose in accordance with the prescribed dosing recommendations, without doubling the amount of the drug.
Patients With Kidney Failure
According to the pharmacokinetics data, the patients suffering from impaired renal function of mild and moderate severity (creatinine clearance 30-80 ml / min) are not required to reduce the dosage. The appointment of Ibuprofen is contraindicated to the patients with high renal failure (creatinine clearance <30 ml / min).
Patients With Liver Failure
If the patients have an impaired liver function of mild and moderate severity of the disease, so the dose reduction is not required (the use in severe liver failure is contraindicated).
Patients with preserved kidney function are not required special dose adjustment. However, taking into consideration the fact that older people are at an increased risk of serious side effects, it is recommended to prescribe the lowest effective therapeutic doses at the minimum time. During the human’s interaction with the drug, regular monitoring is necessary to prevent the occurrence of gastrointestinal bleeding. If the kidney function is impaired, the dosage should be selected individually. If it is necessary to take the drug for more than 7 days, regular monitoring of kidney function is compulsory.
Taking into consideration the fact that the maximum daily dose of Ibuprofen within children is 20 mg / kg, it is inappropriate to prescribe Ibuprofen in 400 mg tablets to children and adolescents weighing less than 40 kg and under the age of 12 years.
If adults, children and adolescents aged from 12 to 18 years are required to use Ibuprofen for more than 3 days or if the symptoms of the disease are increased, it is necessary to consult a doctor.